Cerium(III) chloride → 2-Nitrocinnamyl alcohol
反応式
[BH4-].[Na+].[N+:3]([C:6]1[CH:15]=[CH:14][CH:13]=[CH:12][C:7]=1/[CH:8]=[CH:9]/[CH:10]=[O:11])([O-:5])=[O:4].[Cl-].[Ce+3].[Cl-].[Cl-].[NH4+].[Cl-]>CO>[N+:3]([C:6]1[CH:15]=[CH:14][CH:13]=[CH:12][C:7]=1[CH:8]=[CH:9][CH2:10][OH:11])([O-:5])=[O:4]参加物
6
実験手順
Sodium borohydride (1.15 g, 31.1 mmol) was added portionwise to an ice cooled suspension of trans-2-nitrocinnamaldehyde (5.00 g, 28.2 mmol), and cerium (III) chloride (12.61 g, 33.8 mmol) in methanol (140 ml). After stirring at room temperature for 30 minutes the mixture was poured into saturated aqueous NH4Cl (200 ml), extracted with DCM (3×150 ml) and the extacts dried (MgSO4). Filtration and evaporation of the solvent gave the product. (5.03 g, 100%)
後処理
- temperaturecooled
- extractionextracted with DCM (3×150 ml)
- dry with materialthe extacts dried (MgSO4)
- filtrationFiltration and evaporation of the solvent
- customgave the product
出典と根拠
- ORDレコード
- ord-7f8e6c8452c7405fa345d8c5a83e6fdb
- 出典データセット
- uspto-grants-2000_05
- 特許番号
- US06057311
反応ノート
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