Benzyl Alcohol → 7-Benzyloxy-1-(2-butenyl)-2,3-dimethylpyrrolo[2,3-d]pyridazine

HRID 1107739

反応式

HRID 1107739 の反応式
[CH2:1]([N:5]1[C:9]2=[C:10](Cl)[N:11]=[N:12][CH:13]=[C:8]2[C:7]([CH3:15])=[C:6]1[CH3:16])[CH:2]=[CH:3][CH3:4].[CH2:17]([OH:24])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>>[CH2:17]([O:24][C:10]1[N:11]=[N:12][CH:13]=[C:8]2[C:7]([CH3:15])=[C:6]([CH3:16])[N:5]([CH2:1][CH:2]=[CH:3][CH3:4])[C:9]=12)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1

参加物

3

反応物 2

HCID 244Benzyl AlcoholHCID 537196241-(2-Butenyl)-7-chloro-2,3-dimethylpyrrolo[2,3-d]pyridazine

生成物 1

HCID 536560157-Benzyloxy-1-(2-butenyl)-2,3-dimethylpyrrolo[2,3-d]pyridazine収率 78.6%

実験手順

The title compound (cis/trans=21/79) was prepared as pale brown crystals in 78.6 % yield in a similar procedure to that described in Example 1 by using 1-(2-butenyl)-7-chloro-2,3-dimethylpyrrolo[2,3-d]pyridazine [cis/trans (18/82)] and benzyl alcohol.

出典と根拠

ORDレコード
ord-b75ebdde71a84a9abb646b9bf22a5f04
出典データセット
uspto-grants-2000_05
特許番号
US06063782

関連ノート

読み込み中…