2,6-Dimethylbenzoic acid → 3-(Chlorosulfonyl)-2,6-dimethylbenzoic acid
反応式
[Cl:1][S:2]([OH:5])(=O)=[O:3].[CH3:6][C:7]1[CH:15]=[CH:14][CH:13]=[C:12]([CH3:16])[C:8]=1[C:9]([OH:11])=[O:10]>O>[CH3:6][C:7]1[C:15]([S:2]([Cl:1])(=[O:5])=[O:3])=[CH:14][CH:13]=[C:12]([CH3:16])[C:8]=1[C:9]([OH:11])=[O:10]参加物
4
反応条件
- 温度
- 55 °C
実験手順
4 ml of chlorosulfonic acid are added slowly to 1 g (0.067 mol) of 2,6-dimethylbenzoic acid and the reaction mixture is stirred for 1 hour at 55° C. After cooling, the mixture is poured into 100 ml of iced water. The precipitate formed is filtered off, washed with cold water and then dried in a desiccator under vacuum to give 1.22 g of the expected product in the form of a white solid (yield=73%).
後処理
- temperatureAfter cooling
- customThe precipitate formed
- filtrationis filtered off
- washwashed with cold water
- customdried in a desiccator under vacuum
出典と根拠
- ORDレコード
- ord-c916df01ab0a4736a6e5e0b5b8525a9b
- 出典データセット
- uspto-grants-2000_05
- 特許番号
- US06063791
反応ノート
読み込み中…