Hydroxyamine hydrochloride → HCID 73192201、化合物
反応式
C([O-])(=O)C.[Na+].[CH3:6][C:7]1[CH:16]=[C:15]([CH3:17])[CH:14]=[C:13]2[C:8]=1[C:9](=O)[CH2:10][CH2:11][S:12]2.Cl.[NH2:20][OH:21]>O.C(O)C>[CH3:6][C:7]1[CH:16]=[C:15]([CH3:17])[CH:14]=[C:13]2[C:8]=1[C:9](=[N:20][OH:21])[CH2:10][CH2:11][S:12]2参加物
6
実験手順
A suspension of 37.8 g of sodium acetate in water is added, at 50-60° C., to a suspension of 31.1 g (0.154 mol) of 5,7-dimethylthio-chroman-4-one and 18.5 g (0.261 mol) of hydroxylamine hydrochloride in 200 ml of ethanol. This mixture is subsequently refluxed for 30 minutes. After cooling, filtration with suction of the solid which has precipitated gives 22.2 g of 5,7-dimethylthiochroman-4-one oxime (66% of theory, purity approx. 95%) of melting point 170-174° C.
後処理
- temperatureThis mixture is subsequently refluxed for 30 minutes
- temperatureAfter cooling
- filtrationfiltration with suction of the solid which
- customhas precipitated
出典と根拠
- ORDレコード
- ord-5c5e5b9bad72448cbe0d28df827e6962
- 出典データセット
- uspto-grants-2000_05
- 特許番号
- US06069114
反応ノート
読み込み中…