Trifluoroacetic acid → Trifluoroacetic acid
反応式
C(OC([N:8]1[CH2:13][CH2:12][N:11]([CH2:14][CH2:15][O:16][CH3:17])[C:10](=[O:18])[CH2:9]1)=O)(C)(C)C.[F:19][C:20]([F:25])([F:24])[C:21]([OH:23])=[O:22]>ClCCl>[CH3:17][O:16][CH2:15][CH2:14][N:11]1[CH2:12][CH2:13][NH:8][CH2:9][C:10]1=[O:18].[F:19][C:20]([F:25])([F:24])[C:21]([OH:23])=[O:22]参加物
5
実験手順
1-tert-Butoxycarbonyl-4-(2-methoxyethyl)-3-oxopiperazine (6.6 g) was dissolved in dichloromethane (100 ml), the resulting solution cooled in an ice-bath, and trifluoroacetic acid (145 ml) added. The mixture was stirred at the same temperature for 2 hours. Solvent was evaporated to yield 1-(2-methoxyethyl)-2-oxopiperazine product as a salt with 4 moles of trifluoroacetic acid.
後処理
- temperaturethe resulting solution cooled in an ice-bath
- customSolvent was evaporated
出典と根拠
- ORDレコード
- ord-117ad0c4e71b48be83af6f77d8b15cb8
- 出典データセット
- uspto-grants-2000_05
- 特許番号
- US06069145
反応ノート
読み込み中…