Hypochlorous Acid → N-chloro-2-ethylhexyl carboxamide

HRID 1109267

反応式

HRID 1109267 の反応式
[CH2:1]([CH:3]([CH2:8][CH2:9][CH2:10][CH3:11])[CH2:4][C:5]([NH2:7])=[O:6])[CH3:2].[Cl:12]O>C(OCC)(=O)C>[Cl:12][NH:7][C:5]([CH2:4][CH:3]([CH2:1][CH3:2])[CH2:8][CH2:9][CH2:10][CH3:11])=[O:6]

参加物

4

反応物 2

HCID 24341Hypochlorous AcidHCID 126142952-Ethylhexyl carboxamide

生成物 1

HCID 19022272N-chloro-2-ethylhexyl carboxamide収率 98%

試薬・触媒・溶媒 1

HCID 8857Ethyl Acetate溶媒

実験手順

2-ethylhexyl carboxamide (35.75 g, 250 mmol) was suspended in 300 ml of ethyl acetate and cooled to 1°. Hypochlorous acid (43.3 g of 30.6% solution, 252 m mol) was added dropwise over 13 minutes with stirring. After 10 minutes, the cooling bath was removed and stirring continued for 1 hour while the mixture warmed to room temperature. The ethyl acetate layer was then separated and dried (MgSO4) and the solvent was removed on the rotary evaporator and, finally, on the vacuum pump to give 44 g (98%) of colorless liquid N-chloro-2-ethylhexyl carboxamide.

後処理

  1. temperaturecooled to 1°
  2. customthe cooling bath was removed
  3. stirringstirring
  4. waitcontinued for 1 hour while the mixture
  5. customThe ethyl acetate layer was then separated
  6. dry with materialdried (MgSO4)
  7. customthe solvent was removed on the rotary evaporator

出典と根拠

ORDレコード
ord-375172837e9046319c78f51387520bbe
出典データセット
uspto-grants-1994_06
特許番号
US05319133

関連ノート

読み込み中…