Hypochlorous Acid (HCID 24341)

概要

Hypochlorous acid is a chlorine oxoacid with formula HOCl; a weak, unstable acid, it is the active form of chlorine in water. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor, an EC 2.5.1.18 (glutathione transferase) inhibitor and a human metabolite. It is a member of reactive oxygen species and a chlorine oxoacid. It is a conjugate acid of a hypochlorite.

名称と識別子

優先名称: Hypochlorous Acid
IUPAC: hypochlorous acid
英語名: Hypochlorous acid
分子式: ClHO
分子量: 52.46

名称と別名

HYPOCHLOROUS ACID7790-92-3HClOHOClchloranolComfosyhydroxidochlorinehypochloric acid712K4CDC10DTXSID3036737CHEBI:24757hypochlrous

名称をさらに表示

ChampuregreenDeodorizerLeucillinSufiyaMediaqua premiumDr.DevirusHi CleanerVIRURcatcher

データベース識別子

CAS: 14380-61-1、7790-92-3
PubChem CID: 24341
DTXSID: DTXSID3036737
ChEMBL: CHEMBL1616046
ChEBI: CHEBI:24757
UNII: 712K4CDC10
EC Number: 232-232-5
Nikkaji: J202.839E

物性

構造計算による物性

XLogP: 0.3
極性表面積: 20.2 Å²
水素結合供与体数: 1
水素結合受容体数: 1
回転可能結合数: 0
重原子数: 2
形式電荷: 0
複雑度: 2

実験および物理化学的性質

Chemical ClassesToxic Gases & Vapors -> Acids, Inorganic

SpringerMaterials PropertiesSchoenflies notation

Food Contact Substances · 6 件

FCS -> FDA Inventory of Food Contact Substances Listed in 21 CFR

FCS -> FDA Inventory of Effective Food Contact Substance (FCS) Notifications

Physical Description · 3 件

Liquid

Found only in aqueous solution; Greenish-yellow liquid; [Merck Index] Very unstable; [Hawley] Decomposes exothermically to HCl and O2; [Ullmann]

Solid

物理化学的性質

沸点: 125 · 125-130 °C(Press: 11 Torr)
比重(密度): 1.1655 g/cm3 · 1.1655 g/cm3
酸解離定数(Pka): 7.54 · 7.54±0.10(Predicted)

安全と法規制

GHS分類

GHS ClassificationNot Classified

危険有害性情報

Regulatory Information · 2 件

Hypochlorous acid is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Hypochlorous acid are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Hypochlorous acid: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Hazards Summary · 1 件

A strong oxidizing agent; [Merck Index] A skin and eye irritant; Weak and unstable acid--exists only in dilute solutions; [Hawley] Hypochlorites are used as bleaching agents and disinfectants (swimming pools); they are derived from hypochlorous acid. Hypochlorites have caused hand, diffuse, or periulcerous dermatitis . . . [Kanerva, p. 1803-4] See Hydrogen chloride.

Hazard Classes and CategoriesNot Classified

化学と産業

薬理情報

MeSH Pharmacological ClassificationElectron-accepting molecules in chemical reactions in which electrons are transferred from one molecule to another (OXIDATION-REDUCTION).

用途と製造

Uses · 2 件

Used as a disinfectant; [Merck Index] Used for textile and fiber bleaching, for water purification, and as an antiseptic; [Hawley] Not used much because of its instability; Hypochlorites are used instead in drinking water and swimming pools; [Ullmann]

Pulp and Paper Processing [Category: Industry]

U.S. Production2023: 100,000,000 - <500,000,000 lb

Industry UsesOxidizing agent

Household ProductsInformation on 4 consumer products that contain Hypochlorous acid in the following categories is provided:

General Manufacturing Information · 2 件

All Other Basic Organic Chemical Manufacturing

Hypochlorous acid: ACTIVE