3-Acetylpyridine → 1-[[[[1-(3-Pyridinyl)ethylidene]hydrazino]carbonyl]-methyl]pyridinium chloride
反応式
[CH:1]1[CH:6]=[CH:5][N+:4]([CH2:7][C:8]([NH:10][NH2:11])=[O:9])=[CH:3][CH:2]=1.[Cl-:12].[C:13]([C:16]1[CH:17]=[N:18][CH:19]=[CH:20][CH:21]=1)(=O)[CH3:14]>CO>[Cl-:12].[N:18]1[CH:19]=[CH:20][CH:21]=[C:16]([C:13](=[N:11][NH:10][C:8]([CH2:7][N+:4]2[CH:3]=[CH:2][CH:1]=[CH:6][CH:5]=2)=[O:9])[CH3:14])[CH:17]=1参加物
4
実験手順
To 5.63 gm (0.03 mole) of Girard's Reagent P in 50 ml of anhydrous methanol is added 3.63 gm (0.03 mole) of 3-acetylpyridine. The solution is refluxed 3 hr and cooled. The solvent is evaporated The residue is slurried in 100 ml of anhydrous ether and filtered. The crude product is recrystallized from absolute ethanol to afford 6.18 gm (71%) of the title compound; mp 237.2° (decomp).