Hydrofluoric Acid → 2-(4-Methylphenyl)-2-phenylhexafluoropropane

HRID 1111262

反応式

HRID 1111262 の反応式
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](O)([C:13]([F:16])([F:15])[F:14])[C:9]([F:12])([F:11])[F:10])=[CH:4][CH:3]=1.F>C1C=CC=CC=1>[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)([C:13]([F:16])([F:15])[F:14])[C:9]([F:12])([F:11])[F:10])=[CH:4][CH:3]=1

参加物

4

反応物 2

HCID 14917Hydrofluoric Acid2 回HCID 748292-(p-Tolyl)hexafluoroisopropanol

生成物 1

HCID 147667062-(4-Methylphenyl)-2-phenylhexafluoropropane

試薬・触媒・溶媒 1

HCID 241Benzene溶媒

実験手順

1290 g of 2-(4-methylphenyl)hexafluoropropan-2-ol and 780 g of benzene were placed in a 5-liter steel autoclave and 1500 g of anhydrous hydrogen fluoride was pumped into the sealed autoclave. The reaction mixture was heated at 170°-175° C. with stirring for 64 hours. After completion of the reaction, hydrogen fluoride gas was allowed to escape at 80° C., and the liquid product was then washed twice with water, dried over calcium chloride, and fractionally distilled. Boiling point 135°-136° C./1.4 mbar. Yield: 1424 g (89.5%).

後処理

  1. temperatureThe reaction mixture was heated at 170°-175° C.
  2. customto escape at 80° C.
  3. washthe liquid product was then washed twice with water
  4. dry with materialdried over calcium chloride
  5. distillationfractionally distilled

出典と根拠

ORDレコード
ord-af14167cc71649f3a9a44611fa55aa09
出典データセット
uspto-grants-1990_12
特許番号
US04978742

関連ノート

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