Hydrochloric Acid → HCID 178442823、化合物

HRID 1112136ノート

反応式

HRID 1112136 の反応式
Cl[C:2]1[C:11](=[O:12])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4](=[O:13])[C:3]=1[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25].[OH-:26].[Na+].Cl>C(O)C>[CH2:14]([C:3]1[C:4](=[O:13])[C:5]2[C:10]([C:11](=[O:12])[C:2]=1[OH:26])=[CH:9][CH:8]=[CH:7][CH:6]=2)[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25]

参加物

5

反応物 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 1030502-Chloro-3-dodecyl-1,4-naphthoquinone

生成物 1

HCID 178442823HCID 178442823、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

A mixture of 10 parts of 3-chloro-2-n-dodecyl-1,4-naphthoquinone, 5 parts of 50% aqueous sodium hydroxide and 320 parts of 95% aqueous ethanol were heated at reflux for 15 minutes. The color of the mixture turned from yellow to dark red. The mixture was cooled to 25° and acidified with 10% aqueous hydrochloric acid. The color of the mixture was golden yellow after acidification. The product was filtered off and washed twice with water (25 parts) and twice with cold methanol (25 parts) to yield 8 parts of 2-n-dodecyl-3-hydroxy-1,4-naphthoquinone, mp. 85°-87° C.

後処理

  1. temperaturewere heated
  2. temperatureat reflux for 15 minutes
  3. temperatureThe mixture was cooled to 25°
  4. filtrationThe product was filtered off
  5. washwashed twice with water (25 parts) and twice with cold methanol (25 parts)

出典と根拠

ORDレコード
ord-b09f234e260c40bf93b502016dc24170
出典データセット
uspto-grants-1978_10
特許番号
US04120897

反応ノート

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