Dimethyl Sulfoxide → 7-(2-Chloro-6-fluorobenzyl)-1,3-dimethyl-8-pyrrolidin-1-yl-3,7-dihydro-1H-purine-2,6-dione

反応式

[Br:1][c:2]1[n:3][c:4]2[n:5]([CH3:23])[c:6](=[O:22])[n:7]([CH3:21])[c:8](=[O:20])[c:9]2[n:10]1[CH2:11][c:12]1[c:13]([Cl:19])[cH:14][cH:15][cH:16][c:17]1[F:18].[CH2:24]1[CH2:25][CH2:26][NH:27][CH2:28]1.[CH3:30][S:31]([CH3:32])=[O:33].[OH2:29]>>[c:2]1([N:27]2[CH2:26][CH2:25][CH2:24][CH2:28]2)[n:3][c:4]2[n:5]([CH3:23])[c:6](=[O:22])[n:7]([CH3:21])[c:8](=[O:20])[c:9]2[n:10]1[CH2:11][c:12]1[c:13]([Cl:19])[cH:14][cH:15][cH:16][c:17]1[F:18]