Benzene → 1,2-Epoxy-3-tridecanol
反応式
[CH2:1]=[CH:2][CH:3]([OH:14])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13].ClC1C=CC=C(C(OO)=[O:23])C=1.C1C=CC=CC=1>CCCCCC>[O:23]1[CH:2]([CH:3]([OH:14])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13])[CH2:1]1参加物
5
実験手順
A 500-ml flask equipped with a stirrer was charged with 23.8 g (0.12 mol) of 1-tridecen-3-ol, 25.0 g (0.145 mol) of m-chloroperbenzoic acid and 250 ml of benzene, and the contents were stirred at room temperature for 48 hours. After completion of the reaction, 200 ml of hexane. Solids deposited were separated by filtration, and the solvent was distilled off under reduced pressure. The resultant residue was purified by column chromatography on silica gel, thereby obtaining 19.0 g (yield: 74%) of 1,2-epoxy-3-tridecanol.
後処理
- customA 500-ml flask equipped with a stirrer
- customSolids deposited were separated by filtration
- distillationthe solvent was distilled off under reduced pressure
- customThe resultant residue was purified by column chromatography on silica gel
出典と根拠
- ORDレコード
- ord-336388df5b80425486bbf74ea75cd7c9
- 出典データセット
- uspto-grants-1998_03
- 特許番号
- US05723497
反応ノート
読み込み中…