Benzene → 1,2-Epoxy-3-tridecanol

HRID 1120

反応式

HRID 1120 の反応式
[CH2:1]=[CH:2][CH:3]([OH:14])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13].ClC1C=CC=C(C(OO)=[O:23])C=1.C1C=CC=CC=1>CCCCCC>[O:23]1[CH:2]([CH:3]([OH:14])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13])[CH2:1]1

参加物

5

反応物 3

HCID 241BenzeneHCID 70297m-Chloroperbenzoic acidHCID 185797Tridec-1-en-3-ol

生成物 1

HCID 134206171,2-Epoxy-3-tridecanol収率 74%

試薬・触媒・溶媒 1

HCID 8058Hexane溶媒

実験手順

A 500-ml flask equipped with a stirrer was charged with 23.8 g (0.12 mol) of 1-tridecen-3-ol, 25.0 g (0.145 mol) of m-chloroperbenzoic acid and 250 ml of benzene, and the contents were stirred at room temperature for 48 hours. After completion of the reaction, 200 ml of hexane. Solids deposited were separated by filtration, and the solvent was distilled off under reduced pressure. The resultant residue was purified by column chromatography on silica gel, thereby obtaining 19.0 g (yield: 74%) of 1,2-epoxy-3-tridecanol.

後処理

  1. customA 500-ml flask equipped with a stirrer
  2. customSolids deposited were separated by filtration
  3. distillationthe solvent was distilled off under reduced pressure
  4. customThe resultant residue was purified by column chromatography on silica gel

出典と根拠

ORDレコード
ord-336388df5b80425486bbf74ea75cd7c9
出典データセット
uspto-grants-1998_03
特許番号
US05723497

関連ノート

読み込み中…