Trifluoroacetic acid → N-(3-fluoro-4-(3-(3-(methylcarbamoyl)phenyl)-1H-pyrazolo[3,4-b]pyridin-4-yloxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide

反応式

[F:1][c:2]1[cH:3][c:4]([N:37]([C:38](=[O:39])[C:40]2([C:43](=[O:44])[NH2:45])[CH2:41][CH2:42]2)[c:46]2[cH:47][cH:48][c:49]([F:52])[cH:50][cH:51]2)[cH:5][cH:6][c:7]1[O:8][c:9]1[c:10]2[c:11]([n:12][cH:13][cH:14]1)[n:15]([CH2:28][c:29]1[cH:30][cH:31][c:32]([O:33][CH3:34])[cH:35][cH:36]1)[n:16][c:17]2-[c:18]1[cH:19][c:20]([C:24]([NH:25][CH3:26])=[O:27])[cH:21][cH:22][cH:23]1.[F:53][C:54]([F:55])([F:56])[C:57]([OH:58])=[O:59]>>[F:1][c:2]1[cH:3][c:4]([N:37]([C:38](=[O:39])[C:40]2([C:43](=[O:44])[NH2:45])[CH2:41][CH2:42]2)[c:46]2[cH:47][cH:48][c:49]([F:52])[cH:50][cH:51]2)[cH:5][cH:6][c:7]1[O:8][c:9]1[c:10]2[c:11]([n:12][cH:13][cH:14]1)[nH:15][n:16][c:17]2-[c:18]1[cH:19][c:20]([C:24]([NH:25][CH3:26])=[O:27])[cH:21][cH:22][cH:23]1