Benzyl Bromide → 7-(1-Adamantyl)-6-benzyloxy-2-bromonaphthalene

反応式

[C:1]12([C:11]3[CH:20]=[C:19]4[C:14]([CH:15]=[CH:16][C:17]([Br:21])=[CH:18]4)=[CH:13][C:12]=3[OH:22])[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2.[CH2:23](Br)[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1>>[C:1]12([C:11]3[CH:20]=[C:19]4[C:14]([CH:15]=[CH:16][C:17]([Br:21])=[CH:18]4)=[CH:13][C:12]=3[O:22][CH2:23][C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)[CH2:8][CH:7]3[CH2:9][CH:3]([CH2:4][CH:5]([CH2:6]3)[CH2:10]1)[CH2:2]2

参加物

反応物 2

HCID 7498Benzyl Bromide

HCID 145490723-(Adamantan-1-yl)-6-bromonaphthalen-2-ol

生成物 1

HCID 220003597-(1-Adamantyl)-6-benzyloxy-2-bromonaphthalene収率 80%

実験手順

Following the basic procedure of Example 11, by reacting 12.5 g (35 mmol) of 7-(1-adamantyl)-6-hydroxy-2-bromonaphthalene with 5 ml (42 mmol) of benzyl bromide, 12.5 g (80%) of the expected compound of melting point 150°-151° C. were obtained.

出典と根拠

ORDレコード: ord-b7fc3759f58e4209a7cf0781050443b3
出典データセット: uspto-grants-1998_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05723499

反応ノート

読み込み中…