Chloride → 2-(1,3-dimethyl-1H-pyrazol-4-yl)-5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazine-7-carbaldehyde

HRID 113650ノート

反応式

HRID 113650 の反応式
[Br:19][c:20]1[n:21][c:22]2[c:23]([n:24][cH:25]1)[n:26]([CH2:31][O:32][CH2:33][CH2:34][Si:35]([CH3:36])([CH3:37])[CH3:38])[cH:27][c:28]2[CH:29]=[O:30].[CH3:1][n:2]1[n:3][c:4]([CH3:16])[c:5]([B:7]2[O:8][C:9]([CH3:10])([CH3:11])[C:12]([CH3:13])([CH3:14])[O:15]2)[cH:6]1.[CH3:39][CH2:40][OH:41].[CH3:42][CH2:43][O:44][C:45](=[O:46])[CH3:47].[CH3:49][c:50]1[cH:51][cH:52][cH:53][cH:54][cH:55]1.[Cl-:18].[Li+:17].[OH2:48]>>[CH3:1][n:2]1[n:3][c:4]([CH3:16])[c:5](-[c:20]2[n:21][c:22]3[c:23]([n:24][cH:25]2)[n:26]([CH2:31][O:32][CH2:33][CH2:34][Si:35]([CH3:36])([CH3:37])[CH3:38])[cH:27][c:28]3[CH:29]=[O:30])[cH:6]1

参加物

9

反応物 8

HCID 312ChlorideHCID 702EthanolHCID 962WaterHCID 1140TolueneHCID 8857Ethyl AcetateHCID 28486Lithium ionHCID 426473161,3-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazoleHCID 578296122-bromo-5-((2-(trimethylsilyl)ethoxy)methyl)-5H-pyrrolo[2,3-b]pyrazine-7-carbaldehyde

生成物 1

HCID 584385862-(1,3-dimethyl-1H-pyrazol-4-yl)-5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazine-7-carbaldehyde

出典と根拠

ORDレコード
ord-02d26e5d824d4a30a551a3cd66e354bd
出典データセット
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

反応ノート

読み込み中…