Tetrahydrofuran → N-(1-Benzo[b]thiophen-3-ylmethyl-2,2,2-trifluoroethyl)-2,4,6-trimethylbenzenesulfonamide

反応式

[Br:2][c:3]1[c:4]2[c:5]([s:6][cH:7]1)[cH:8][cH:9][cH:10][cH:11]2.[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[Cu:36][I:37].[F:12][C:13]([CH:14]1[N:15]([S:17](=[O:18])(=[O:19])[c:20]2[c:21]([CH3:28])[cH:22][c:23]([CH3:27])[cH:24][c:25]2[CH3:26])[CH2:16]1)([F:29])[F:30].[Mg:1]>>[c:3]1([CH2:16][CH:14]([C:13]([F:12])([F:29])[F:30])[NH:15][S:17](=[O:18])(=[O:19])[c:20]2[c:21]([CH3:28])[cH:22][c:23]([CH3:27])[cH:24][c:25]2[CH3:26])[c:4]2[c:5]([s:6][cH:7]1)[cH:8][cH:9][cH:10][cH:11]2