Tetrahydrofuran → 3-Amino-5-trifluoromethyl-indazole-1-carboxylic acid tert-butylamide

反応式

[C:1]([CH3:2])([CH3:3])([CH3:4])[NH:5][C:6](=[O:7])[n:8]1[n:9][c:10]([N:21]2[C:22](=[O:23])[c:24]3[c:25]([cH:26][cH:27][cH:28][cH:29]3)[C:30]2=[O:31])[c:11]2[cH:12][c:13]([C:17]([F:18])([F:19])[F:20])[cH:14][cH:15][c:16]12.[CH2:34]1[O:35][CH2:36][CH2:37][CH2:38]1.[NH2:32][NH2:33]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[NH:5][C:6](=[O:7])[n:8]1[n:9][c:10]([NH2:21])[c:11]2[cH:12][c:13]([C:17]([F:18])([F:19])[F:20])[cH:14][cH:15][c:16]12

参加物

反応物 3

HCID 8028Tetrahydrofuran

HCID 9321Hydrazine

HCID 585487433-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-5-trifluoromethyl-indazole-1-carboxylic acid tert-butyl amide

生成物 1

HCID 585487953-Amino-5-trifluoromethyl-indazole-1-carboxylic acid tert-butylamide

出典と根拠

ORDレコード: ord-fa6d534f2eb7467da18673cecf9fb3d4
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…