1-Butanol → Benzenepropanol
反応式
[CH2:1]([OH:5])[CH2:2][CH2:3][CH3:4].ClCl.Cl[CH:9](Cl)[CH:10](Cl)Cl.Cl[C:15](Cl)([CH2:18]C)[CH:16]=O>CN(C=O)C.Cl.C(O)C(C)C>[C:4]1([CH2:3][CH2:2][CH2:1][OH:5])[CH:10]=[CH:9][CH:18]=[CH:15][CH:16]=1参加物
7
実験手順
n-Butanol and Cl2 were added concurrently to a 100 ml, four necked, round bottomed flask containing ~10 g of DMF/HCl catalyst and 25 ml of 1,1,2,2-tetrachloroethane. The temperature was maintained between 50° and 55° C. by controlling the rates of the addition. Upon completion of the addition, the reaction mixture was shown to contain mainly the product 2,2-dichlorobutyraldehyde by GC and NMR analysis. Similar results were obtained with isobutanol and 3-phenylpropanol. Analysis was in agreement with authentic products by GC, IR and NMR.
後処理
- temperatureThe temperature was maintained between 50° and 55° C.
- additionthe rates of the addition
- additionUpon completion of the addition
- customSimilar results
出典と根拠
- ORDレコード
- ord-58577cdad3b14dbdae74e7181a87f133
- 出典データセット
- uspto-grants-1984_12
- 特許番号
- US04486608
反応ノート
読み込み中…