Hydrochloric Acid → HCID 20434988、化合物
反応式
Br[CH2:2][C:3]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)=O.C([NH:14][NH:15][C:16]([NH2:18])=[O:17])(=O)C.[ClH:19]>C(O)C>[ClH:19].[NH:15]([C:16]1[O:17][CH:2]=[C:3]([C:5]2[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=2)[N:18]=1)[NH2:14]参加物
5
実験手順
A solution of α-bromoacetophenone (19.9 g) and acetylsemicarbazide (10.7 g) in ethanol (300 ml), containing 1N hydrochloric acid (1 ml), was refluxed for thirty hours. The solvent was removed in vacuo and the residue was crystallized from ether-ethanol to give 2-hydrazino-4-phenyloxazole hydrochloride. This salt was suspended in an aqueous solution of 10% ammonium hydroxide to give 2-hydrazino-4-phenyloxazole, m.p. 158°-160° C.
後処理
- temperaturewas refluxed for thirty hours
- customThe solvent was removed in vacuo
- customthe residue was crystallized from ether-ethanol
出典と根拠
- ORDレコード
- ord-1ded7daa9b324099bb4ce3130b060fb1
- 出典データセット
- uspto-grants-1984_12
- 特許番号
- US04489084
反応ノート
読み込み中…