Ethanolamine → HCID 86738096、化合物

HRID 1155103

反応式

HRID 1155103 の反応式
[C:1]([NH:4][C@H:5]([C:16]([OH:18])=[O:17])[CH2:6][C:7]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[NH:9][CH:8]=1)(=[O:3])[CH3:2].[CH2:19]([CH2:21][NH2:22])[OH:20]>C(O)C>[C:1]([NH:4][C@H:5]([C:16]([OH:18])=[O:17])[CH2:6][C:7]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[NH:9][CH:8]=1)(=[O:3])[CH3:2].[CH2:19]([CH2:21][NH2:22])[OH:20]

参加物

4

反応物 2

HCID 700EthanolamineHCID 700653N-Acetyl-L-tryptophan

生成物 1

HCID 86738096HCID 86738096、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

反応条件

温度
70 °C

実験手順

50 g of absolute ethyl alcohol and 24.6 g (0.1 mol) of N-acetyl tryptophan (DL) were mixed in a 250-ml three-necked flask, yielding a rather thick paste. 6.5 g (0.107 M) of monoethanolamine was added; the mixture dissolved rapidly, after which the salt was observed to crystallise. The mixture was heated to 70° C. for 30 minutes and cooled to 20° C. The crystals (colourless) were thoroughly centrifuged, washed in ethyl ether and dried at 50° C.

後処理

  1. customyielding a rather thick paste
  2. dissolutionthe mixture dissolved rapidly
  3. customto crystallise
  4. temperaturecooled to 20° C
  5. washwashed in ethyl ether
  6. customdried at 50° C.

出典と根拠

ORDレコード
ord-7059ae5d7fab4ec6b83a7eb17e211586
出典データセット
uspto-grants-1981_11
特許番号
US04299838

関連ノート

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