Tiopronin → HCID 56608455、化合物

HRID 1155144

反応式

HRID 1155144 の反応式
[SH:1][CH:2]([CH3:10])[C:3]([NH:5][CH2:6][C:7]([OH:9])=[O:8])=[O:4].[C:11]1([C:17]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)O)[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>FC(F)(F)C(O)=O>[C:17]([S:1][CH:2]([CH3:10])[C:3]([NH:5][CH2:6][C:7]([OH:9])=[O:8])=[O:4])([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)([C:25]1[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=1)[C:19]1[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=1

参加物

4

反応物 2

HCID 5483TioproninHCID 6457Triphenylcarbinol

生成物 1

HCID 56608455HCID 56608455、化合物

試薬・触媒・溶媒 1

HCID 6422Trifluoroacetic acid溶媒

実験手順

To a solution of alpha-mercaptopropionyl glycine (50 g; 0.307 moles) in 300 ml of trifluoroacetic acid, were added 79.9 g (0.307 moles) of triphenylcarbinol. The thus obtained solution was kept under stirring at room temperature for 15 minutes. The excess of trifluoroacetic acid was removed by evaporation and the residue taken up with ether. Filtration yielded a white solid, which was then washed with ether and dried in vacuo to constant weight.

後処理

  1. customThe excess of trifluoroacetic acid was removed by evaporation
  2. filtrationFiltration
  3. customyielded a white solid, which
  4. washwas then washed with ether
  5. customdried in vacuo to constant weight

出典と根拠

ORDレコード
ord-c35d75ee4e0a4b42801e8a21fcc5aea0
出典データセット
uspto-grants-1981_11
特許番号
US04299842

関連ノート

読み込み中…