Formaldehyde → 2-Nitrotoluene

HRID 1155209

反応式

HRID 1155209 の反応式
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[CH3:10])([O-:3])=[O:2].[CH2:11]=[O:12].[OH-:13].[K+].[CH3:15]N(C)C=O>O>[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[CH:11]([OH:12])[CH3:15])([O-:2])=[O:13].[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[CH3:10])([O-:3])=[O:2]

参加物

7

反応物 4

HCID 712FormaldehydeHCID 6228DimethylformamideHCID 69442-NitrotolueneHCID 14797Potassium Hydroxide

生成物 2

HCID 69442-NitrotolueneHCID 978511-(2-Nitrophenyl)ethanol

試薬・触媒・溶媒 1

HCID 962Water溶媒

反応条件

温度
30 °C

実験手順

A mixture of 137 g (1 mole) of o-nitrotoluene, 120 g of paraformaldehyde, 34 g of potassium hydroxide and 500 ml of dimethyl formamide containing 0.7% by weight of water is stirred at 30° C. for 1.5 hours and then at 55° C. for 1 hour. The reaction mixture is processed as described in Example 1 to obtain 35 g of o-nitrophenylethanol, 20 g of o-nitrotoluene and 35 g of bis-methylol compounds. The bis-methylol compounds were identified by gas chromatographical mass spectrum (GCMS) analysis.

後処理

  1. waitat 55° C. for 1 hour

出典と根拠

ORDレコード
ord-8656c1d09c184b4da34a03225db3f9b9
出典データセット
uspto-grants-1981_11
特許番号
US04299992

関連ノート

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