Ethanol → HCID 54522879、化合物
反応式
[C:1]([OH:8])(=[O:7])[CH2:2][CH2:3][C:4]([CH3:6])=O.Cl.[F:10][C:11]([F:21])([F:20])[C:12]1[CH:17]=[CH:16][C:15]([NH:18]N)=[CH:14][CH:13]=1.[CH2:22](O)[CH3:23].S(=O)(=O)(O)O>O>[CH2:22]([O:8][C:1](=[O:7])[CH2:2][C:3]1[C:16]2[C:15](=[CH:14][CH:13]=[C:12]([C:11]([F:21])([F:20])[F:10])[CH:17]=2)[NH:18][C:4]=1[CH3:6])[CH3:23]参加物
6
実験手順
A stirred mixture of 11.6 g. of levulinic acid, 21.3 g. of 4-trifluoromethylphenylhydrazine hydrochloride, 125 ml. of ethanol and 10 ml. of concentrated sulfuric acid is heated under reflux for 24 hours. The reaction mixture is poured onto chopped ice and water. A precipitate forms and is collected by filtration to give ethyl-2-methyl-5-trifluoromethyl-3-indoleacetate.
後処理
- additionA stirred mixture of 11.6 g
- temperatureunder reflux for 24 hours
- additionThe reaction mixture is poured
- filtrationA precipitate forms and is collected by filtration
出典と根拠
- ORDレコード
- ord-e0846d9dbcda444bbabad44fc22d961a
- 出典データセット
- uspto-grants-1981_11
- 特許番号
- US04302589
反応ノート
読み込み中…