Benzaldehyde → N-benzylidene histidine methyl ester
反応式
[CH3:1][O:2][C:3](=[O:12])[C@H:4]([CH2:6][C:7]1[N:11]=[CH:10][NH:9][CH:8]=1)[NH2:5].[CH:13](=O)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1.[O-]S([O-])(=O)=O.[Mg+2]>C(Cl)(Cl)Cl>[CH3:1][O:2][C:3](=[O:12])[C@H:4]([CH2:6][C:7]1[N:11]=[CH:10][NH:9][CH:8]=1)[N:5]=[CH:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1参加物
5
実験手順
Histidine methyl ester, 185 mg (1 mmole), is treated with 1.06 g (1 mmole) of benzaldehyde in 25 ml of CHCl3 for 3 hours. MgSO4, 0.2 g, is added for the last hour. The mixture is filtered and the solvent is evaporated, to leaving compound 2·I as a residue.
後処理
- filtrationThe mixture is filtered
- customthe solvent is evaporated
- customto leaving compound 2·I as a residue
出典と根拠
- ORDレコード
- ord-23d22fd2f8a342ffa48603272e1c57a8
- 出典データセット
- uspto-grants-1982_06
- 特許番号
- US04332813
反応ノート
読み込み中…