Hydrogen Bromide → HCID 20530721、化合物
反応式
[CH3:1][C:2]1[CH:3]=[C:4]([CH:18]=[CH:19][CH:20]=1)[C:5]([CH:7]1[CH2:12][CH2:11][N:10](C(OCC)=O)[CH2:9][CH2:8]1)=[O:6].[BrH:21]>O>[BrH:21].[CH3:1][C:2]1[CH:3]=[C:4]([C:5]([CH:7]2[CH2:12][CH2:11][NH:10][CH2:9][CH2:8]2)=[O:6])[CH:18]=[CH:19][CH:20]=1参加物
4
実験手順
A mixture of 12 parts of ethyl 4-(3-methylbenzoyl)-1-piperidinecarboxylate and 225 parts of a hydrobromic acid solution 48% in water is stirred and refluxed for 3 hours. The reaction mixture is evaporated and the residue is crystallized from 2-propanol, yielding 7.5 parts of (3-methylphenyl) (4-piperidinyl)methanone hydrobromide.
後処理
- temperaturerefluxed for 3 hours
- customThe reaction mixture is evaporated
- customthe residue is crystallized from 2-propanol
出典と根拠
- ORDレコード
- ord-f2ee6ac8c5e24e49b28dc12deeeeeace
- 出典データセット
- uspto-grants-1982_06
- 特許番号
- US04335127
反応ノート
読み込み中…