Ethyl 3-bromo-2-oxocyclohexanecarboxylate → Ethyl 2-methyl-4,5,6,7-tetrahydrobenzo[d]thiazole-4-carboxylate

反応式

[C:1]([NH2:4])(=[S:3])[CH3:2].Br[CH:6]1[CH2:11][CH2:10][CH2:9][CH:8]([C:12]([O:14][CH2:15][CH3:16])=[O:13])[C:7]1=O>>[CH3:2][C:1]1[S:3][C:6]2[CH2:11][CH2:10][CH2:9][CH:8]([C:12]([O:14][CH2:15][CH3:16])=[O:13])[C:7]=2[N:4]=1

参加物

反応物 2

HCID 121765Ethyl 3-bromo-2-oxocyclohexanecarboxylate

HCID 2723949Thioacetamide

生成物 1

HCID 12917740Ethyl 2-methyl-4,5,6,7-tetrahydrobenzo[d]thiazole-4-carboxylate

実験手順

This compound is prepared by action of thioacetamide on 2-bromo-6-carbethoxy-cyclohexanone (II), according to the process described in Example 1. B.p.0.1 =102°-105° C.

後処理

customB.p.0.1 =102°-105° C.

出典と根拠

ORDレコード: ord-5aaace555378478783f266c723c12df2
出典データセット: uspto-grants-1982_06
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04337343

反応ノート

読み込み中…