Dimethylformamide → (R)-2-(5-((S)-2-(4-Chlorophenyl)propanamido)-1-oxoisoquinolin-2(1H)-yl)-N-cyclopropyl-3-methylbutanamide

反応式

[NH2:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][N:6]([C@H:13]([CH:20]([CH3:22])[CH3:21])[C:14]([NH:16][CH:17]1[CH2:19][CH2:18]1)=[O:15])[C:7]2=[O:12].[Cl:23][C:24]1[CH:29]=[CH:28][C:27]([C@H:30]([CH3:34])[C:31](O)=[O:32])=[CH:26][CH:25]=1.F[P-](F)(F)(F)(F)F.C[N+](C)=C(N(C)C)ON1C2N=CC=CC=2N=N1.C(N(CC)C(C)C)(C)C.CN(C)C=O>C(Cl)Cl>[Cl:23][C:24]1[CH:25]=[CH:26][C:27]([C@H:30]([CH3:34])[C:31]([NH:1][C:2]2[CH:11]=[CH:10][CH:9]=[C:8]3[C:3]=2[CH:4]=[CH:5][N:6]([C@H:13]([CH:20]([CH3:22])[CH3:21])[C:14]([NH:16][CH:17]2[CH2:19][CH2:18]2)=[O:15])[C:7]3=[O:12])=[O:32])=[CH:28][CH:29]=1