1-(3-Chloropropoxy)-2-nitrobenzene → 2-(3-Chloropropoxy)aniline
反応式
[Cl:1][CH2:2][CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[N+:12]([O-])=O.[H][H]>C(O)C.[Pt](=O)=O>[Cl:1][CH2:2][CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[NH2:12]参加物
5
実験手順
1-(3-Chloro-propoxy)-2-nitro-benzene (60 mmol) is dissolved in ethanol (200 ml) and platinum dioxide (0.5 g) is added. The stirred mixture is treated with hydrogen under normal pressure until the hydrogen uptake stopped. The catalyst is filtered off and the filtrate is evaporated. A pale yellow oil with Rf=0.3 (CH2Cl2) is obtained, which is used in the next step without further purification.
後処理
- filtrationThe catalyst is filtered off
- customthe filtrate is evaporated
- customA pale yellow oil with Rf=0.3 (CH2Cl2) is obtained
- customwhich is used in the next step without further purification
出典と根拠
- ORDレコード
- ord-faa0c63dba014a059479c60598ecfc6f
- 出典データセット
- uspto-grants-2010_10
- 特許番号
- US07820818B2
反応ノート
読み込み中…