Chlorosulfonic acid → 2,4,6-Trimethoxybenzene-1-sulfonyl chloride
反応式
[CH3:1][O:2][C:3]1[CH:8]=[C:7]([O:9][CH3:10])[CH:6]=[C:5]([O:11][CH3:12])[CH:4]=1.[Cl:13][S:14](O)(=[O:16])=[O:15]>ClCCl>[CH3:12][O:11][C:5]1[CH:4]=[C:3]([O:2][CH3:1])[CH:8]=[C:7]([O:9][CH3:10])[C:6]=1[S:14]([Cl:13])(=[O:16])=[O:15]参加物
4
実験手順
In 500 ml of dichloromethane is dissolved 5.05 g of 1,3,5-trimethoxybenzene and the solution was cooled to -5°~-10° C. A solution of 6 ml of chlorosulfonic acid in 400 ml of dichloromethane was added dropwise, and the mixture was allowed to stand at room temperature. The reaction mixture was then treated as in Reference Example 1. The resulting product was crystallized from carbon tetrachloride and filtered. Yield 610 mg (6.3%), m.p. 126°-129° C.
後処理
- temperaturethe solution was cooled to -5°~-10° C
- customto stand at room temperature
- additionThe reaction mixture was then treated as in Reference Example 1
- customThe resulting product was crystallized from carbon tetrachloride
- filtrationfiltered
出典と根拠
- ORDレコード
- ord-97908d4f72fc4d4e9c1d12f421265b35
- 出典データセット
- uspto-grants-1983_01
- 特許番号
- US04368150
反応ノート
読み込み中…