Hydrazine hydrate (1:1) → 6-(2-Methyl-1,3-dioxolan-2-yl)hexan-1-amine
反応式
[CH3:1][C:2]1([CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][N:13]2C(=O)C3=CC=CC=C3C2=O)[O:6][CH2:5][CH2:4][O:3]1.O.NN>C(O)C>[CH3:1][C:2]1([CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][NH2:13])[O:3][CH2:4][CH2:5][O:6]1参加物
4
実験手順
A mixture of 125.25 g (0.395 mole) of N-[6-(2-methyl-1,3-dioxolan-2-yl)hexyl]phthalimide, 23 ml of 85% hydrazine hydrate, and 370 ml of 95% ethanol was refluxed for four hours, cooled, filtered and stripped. The residue was mixed with 500 ml of water, basified with 2 N NaOH solution and extracted with methylene chloride. The organic layer was separated, dried over anhydrous potassium carbonate, filtered, and stripped to an orange oil. This material was distilled to give 35.70 g (64%) of clear oil bp 80°-83° (0.100 mm).
後処理
- temperaturewas refluxed for four hours
- temperaturecooled
- filtrationfiltered
- additionThe residue was mixed with 500 ml of water
- extractionextracted with methylene chloride
- customThe organic layer was separated
- dry with materialdried over anhydrous potassium carbonate
- filtrationfiltered
- distillationThis material was distilled
出典と根拠
- ORDレコード
- ord-82eb6438fb3043a6a2c519dfd2fb909c
- 出典データセット
- uspto-grants-1983_01
- 特許番号
- US04370335
反応ノート
読み込み中…