m-Chloroperbenzoic acid → HCID 19757849、化合物

HRID 1164870ノート

反応式

HRID 1164870 の反応式
[CH2:1]([O:3][P:4]([C:9]1[CH:10]=[N:11][CH:12]=[CH:13][CH:14]=1)([O:6][CH2:7][CH3:8])=[O:5])[CH3:2].ClC1C=CC=C(C(OO)=[O:23])C=1>C(Cl)Cl>[CH2:1]([O:3][P:4]([C:9]1[CH:10]=[N+:11]([O-:23])[CH:12]=[CH:13][CH:14]=1)([O:6][CH2:7][CH3:8])=[O:5])[CH3:2]

参加物

4

反応物 2

HCID 70297m-Chloroperbenzoic acidHCID 10867660Diethyl pyridin-3-ylphosphonate

生成物 1

HCID 19757849HCID 19757849、化合物

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

A solution of 1.5 g of 3-diethylphosphonopyridine, Bull. Chem. Soc. Jap. 55, 909 (1982), in 20 ml of methylene chloride is treated with 2.33 g m-chloroperbenzoic acid at room temperature. The reaction mixture is allowed to stir at room temperature overnight, then concentrated under vacuum. The residue is partitioned between ether and water, the aqueous layer is concentrated under vacuum to afford 3-(diethylphosphono)-pyridine-N-oxide as a yellow oil.

後処理

  1. concentrationconcentrated under vacuum
  2. customThe residue is partitioned between ether and water
  3. concentrationthe aqueous layer is concentrated under vacuum

出典と根拠

ORDレコード
ord-fef240fb309c4c0fb2ba15c4b0325317
出典データセット
uspto-grants-1990_03
特許番号
US04906621

反応ノート

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