Ethanol → HCID 22996561、化合物

HRID 1167245ノート

反応式

HRID 1167245 の反応式
C[C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-])=O)=[CH:4][C:3]=1[S:11]([N:14]([CH3:16])[CH3:15])(=[O:13])=[O:12].[CH2:17](O)C>[Pd]>[NH2:8][C:5]1[C:4]([CH3:17])=[C:3]([S:11]([N:14]([CH3:15])[CH3:16])(=[O:12])=[O:13])[CH:2]=[CH:7][CH:6]=1

参加物

4

反応物 2

HCID 702EthanolHCID 2921148N,N,2-trimethyl-5-nitro-Benzenesulfonamide

生成物 1

HCID 22996561HCID 22996561、化合物収率 98%

試薬・触媒・溶媒 1

HCID 23938Palladium触媒

実験手順

A suspension of 2-methyl-5-nitro(N,N-dimethyl)benzenesulfonamide (2.0 g, 8.20 mmol) and Pd/C (0.30 g) in ethanol (40 mL) was stirred under an H2 balloon for 16 h. The suspension was filtered through Celite and washed with methylene chloride. The filtrate was concentrated to provide 3-amino-2-methyl(N,N-dimethyl) benzenesulfonamide (1.72 g, 98%) as a white solid.

後処理

  1. filtrationThe suspension was filtered through Celite
  2. washwashed with methylene chloride
  3. concentrationThe filtrate was concentrated

出典と根拠

ORDレコード
ord-d444b8205b9247d09527fa22a2447c68
出典データセット
uspto-grants-2003_09
特許番号
US06617357B2

反応ノート

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