Triethylamine → HCID 21361363、化合物

HRID 1168576ノート

反応式

HRID 1168576 の反応式
[CH2:1]([C:3]1([CH3:23])[CH:8]([CH3:9])[CH:7]([OH:10])[CH2:6][C:5]([CH2:12][CH3:13])([CH3:11])[N:4]1[O:14][CH:15]([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)[CH3:16])[CH3:2].[C:24](Cl)(=[O:27])[CH:25]=[CH2:26].C(N(CC)CC)C>C1(C)C=CC=CC=1>[CH2:1]([C:3]1([CH3:23])[CH:8]([CH3:9])[CH:7]([O:10][C:24](=[O:27])[CH:25]=[CH2:26])[CH2:6][C:5]([CH2:12][CH3:13])([CH3:11])[N:4]1[O:14][CH:15]([C:17]1[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=1)[CH3:16])[CH3:2]

参加物

5

反応物 3

HCID 8471TriethylamineHCID 13140Acryloyl chlorideHCID 223418512,6-Diethyl-2,3,6-trimethyl-1-(1-phenylethoxy)piperidin-4-ol

生成物 1

HCID 21361363HCID 21361363、化合物収率 870.1%

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

In analogy to example 1 were reacted 6,36 g (2 mmol) of 2,6-diethyl-2,3,6-trimethyl-1-(1-phenyl-ethoxy)-piperidin-4-ol with 1,81 g (2 mmol) of acryloyl chloride and 2.02 g (2 mmol) of triethylamine in toluene to give 6,5 g (87%) acrylic acid 2,6-di-ethyl-2,3,6-trimethyl-1-(1-phenyl-ethoxy)-piperidin-4-yl ester as yellowish liquid. Elemental analysis calculated for C23H35NO3: C 73,95%; H 9,44%; N 3,75%. Found: C 74,43%; H 9,44%; N 3,91%.

出典と根拠

ORDレコード
ord-b4f0980731334d688ce2157764efa813
出典データセット
uspto-grants-2003_09
特許番号
US06624306B2

反応ノート

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