Benzyl Alcohol → HCID 11675537、化合物
反応式
[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([CH2:25][C:26]([OH:28])=[O:27])[CH:12]=[C:13]([C:15]2[CH:20]=[CH:19][C:18]([C:21]([F:24])([F:23])[F:22])=[CH:17][CH:16]=2)[CH:14]=1)[C:2]1[CH:7]=[CH:6]C=CC=1.[CH:29]1(COC2C=C(CC(O)=O)C=C(C3C=CC(C(F)(F)F)=CC=3)C=2)[CH2:31][CH2:30]1.C(O)C1C=CC=CC=1.C1(CO)CC1>>[CH:2]1([CH2:1][O:8][C:9]2[CH:10]=[C:11]([CH:25]([CH2:30][CH2:29][CH3:31])[C:26]([OH:28])=[O:27])[CH:12]=[C:13]([C:15]3[CH:16]=[CH:17][C:18]([C:21]([F:23])([F:22])[F:24])=[CH:19][CH:20]=3)[CH:14]=2)[CH2:6][CH2:7]1参加物
5
実験手順
Procedure as for example 10 replacing (5-benzyloxy-4′-trifluoromethyl-biphenyl-3-yl)-acetic acid with 5-cyclopropylmethoxy-4′-trifluoromethyl-biphenyl-3-yl-acetic acid, itself made according to the procedure of example 9 replacing benzyl alcohol with cyclopropylmethyl alcohol afforded 2-(5-cyclopropylmethoxy-4′-trifluoromethyl-biphenyl-3-yl)-pentanoic acid, LC method B, retention time 12.8 min.