化工社化工社 化学情報印刷レポート · 研究参考用
Stannous Chloride → 2-Amino-5-fluorobenzonitrile
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Stannous Chloride | HCID 24479 | — |
| 反応物 | 5-Fluoro-2-nitrobenzonitrile | HCID 3756467 | — |
| 溶媒 | Hydrochloric Acid | HCID 313 | — |
| 生成物 | 2-Amino-5-fluorobenzonitrile | HCID 2737704 | — |
反応手順
The title compound was synthesized from commercially available 2-nitro-5-fluorobenzenecarbonitrile via reduction with SnCl2 in concentrated HCl as previously described in the following reference which is herein incorporated by reference in its entirety for all purposes as if fully set forth herein: Hunziker, F. et al. Eur. J. Med. Chem., Chim. Ther. 1981, 16(5), 391. GC/MS m/z: 136.1 (M+, 100%), Rt 8.87 minutes.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07825132B2 |
| 出典データセット | uspto-grants-2010_11 |
| ORD ID | ord-01cbccf3425e409f9d5ffa2a1318af5c |
| 出典メモ | uspto-grants-2010_11 |