HCID 12988784、化合物 → 1,2-Benzenediamine, 4-[2-(4-morpholinyl)ethoxy]-

HRID 1169994ノート

反応式

HRID 1169994 の反応式
[N:1]1([CH2:7][CH2:8][O:9][C:10]2[CH:15]=[CH:14][C:13]([NH2:16])=[C:12]([N+:17]([O-])=O)[CH:11]=2)[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1>CCO.[Pd]>[N:1]1([CH2:7][CH2:8][O:9][C:10]2[CH:11]=[C:12]([NH2:17])[C:13]([NH2:16])=[CH:14][CH:15]=2)[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1

参加物

4

反応物 1

HCID 12988784HCID 12988784、化合物

生成物 1

HCID 129887851,2-Benzenediamine, 4-[2-(4-morpholinyl)ethoxy]-

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

To a solution 4-(2-morpholin-4-ylethoxy)-2-nitrophenylamine (1.0 equivalent) in EtOH was added Pd/C (0.1 equivalents). The reaction vessel was repeatedly purged with hydrogen, then stirred under a hydrogen atmosphere (1 atm) for 18 hours. The product was filtered through a Celite plug, and the plug washed with EtOH. The diamine was used without purification. LC/MS m/z 238.3 (MH+), Rt 0.295 minutes.

後処理

  1. customThe reaction vessel was repeatedly purged with hydrogen
  2. filtrationThe product was filtered through a Celite plug
  3. washthe plug washed with EtOH
  4. customThe diamine was used without purification

出典と根拠

ORDレコード
ord-edef0bea0f9842aab20df01c86f3a878
出典データセット
uspto-grants-2010_11
特許番号
US07825132B2

反応ノート

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