反応式
[CH2:1]([O:3][C:4](=[O:17])[CH:5]=[C:6]1[C:14]2[C:9](=[CH:10][CH:11]=[C:12]([O:15][CH3:16])[CH:13]=2)[CH2:8][CH2:7]1)[CH3:2]>CO.[Pd]>[CH2:1]([O:3][C:4](=[O:17])[CH2:5][CH:6]1[C:14]2[C:9](=[CH:10][CH:11]=[C:12]([O:15][CH3:16])[CH:13]=2)[CH2:8][CH2:7]1)[CH3:2]参加物
4
実験手順
(6-methoxy-indan-1-ylidene)-acetic acid ethyl ester (3.18 g, 14.5 mmol) was dissolved in MeOH (30 ml). A catalytic amount of 10% Pd/C was added and the reaction was stirred under an atmosphere of hydrogen (balloon) for 2 h. The reaction mixture was filtered through Celite to provide pure (6-methoxy-indan-1-yl)-acetic acid ethyl ester (2.98 g, 94%) as a clear oil. LCMS: 235.0 (M+1)+.
後処理
- filtrationThe reaction mixture was filtered through Celite
出典と根拠
- ORDレコード
- ord-5808587534624ece9fe7b05eb901f078
- 出典データセット
- uspto-grants-2010_11
- 特許番号
- US07834004B2
関連ノート
読み込み中…