1-Boc-Azetidine-3-carboxylic acid → tert-Butyl 3-[({5-[(6,7-dichloro-1-oxo-1,2-dihydropyrrolo[1,2-a]pyrazin-4-yl)methyl]-2-fluorophenyl}amino)carbonyl]azetidine-1-carboxylate

反応式

[C:1]([N:8]1[CH2:11][CH:10]([C:12]([OH:14])=O)[CH2:9]1)([O:3][C:4]([CH3:7])([CH3:6])[CH3:5])=[O:2].CN(C(ON1N=NC2C=CC=NC1=2)=[N+](C)C)C.F[P-](F)(F)(F)(F)F.FC(F)(F)C([O-])=O.[Cl:46][C:47]1[N:51]2[C:52]([CH2:57][C:58]3[CH:59]=[CH:60][C:61]([F:65])=[C:62]([NH3+:64])[CH:63]=3)=[CH:53][NH:54][C:55](=[O:56])[C:50]2=[CH:49][C:48]=1[Cl:66]>CN(C1C=CN=CC=1)C.CN(C=O)C.O.CC#N>[Cl:46][C:47]1[N:51]2[C:52]([CH2:57][C:58]3[CH:59]=[CH:60][C:61]([F:65])=[C:62]([NH:64][C:12]([CH:10]4[CH2:9][N:8]([C:1]([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])=[O:2])[CH2:11]4)=[O:14])[CH:63]=3)=[CH:53][NH:54][C:55](=[O:56])[C:50]2=[CH:49][C:48]=1[Cl:66]