HCID 12767831、化合物 → 2-Propyl-4-(4-chlorophenoxy)phenol
反応式
[Cl:1][C:2]1[CH:18]=[CH:17][C:5]([O:6][C:7]2[CH:12]=[CH:11][C:10]([OH:13])=[C:9]([CH2:14][CH:15]=[CH2:16])[CH:8]=2)=[CH:4][CH:3]=1>C(OCC)(=O)C.[Pd]>[Cl:1][C:2]1[CH:18]=[CH:17][C:5]([O:6][C:7]2[CH:12]=[CH:11][C:10]([OH:13])=[C:9]([CH2:14][CH2:15][CH3:16])[CH:8]=2)=[CH:4][CH:3]=1参加物
4
実験手順
A mixture of the product from step 4 (15.7 g, 60 mmol) and 10% Pd/C (3.1 g) in ethyl acetate (300 mL) was stirred under hydrogen (1 atm). After the reaction was completed (ca. 30 min), the mixture was filtered through celite and the filtrate was concentrated to give 15.7 g of the title compound as an oil which solidified upon standing.
後処理
- custom(ca. 30 min)
- filtrationthe mixture was filtered through celite
- concentrationthe filtrate was concentrated
出典と根拠
- ORDレコード
- ord-e571cbcda72748c38d02b2a2e1494a82
- 出典データセット
- uspto-grants-2010_11
- 特許番号
- US07834036B2
反応ノート
読み込み中…