反応式
[S:1]([C:5]1[CH:10]=[CH:9][C:8]([S:11](Cl)(=[O:13])=O)=[CH:7][CH:6]=1)(=[O:4])(=[O:3])[NH2:2].N[C:16]1[CH:17]=[CH:18][CH:19]=[C:20]2[C:24]=1[NH:23][CH:22]=[CH:21]2>>[NH:23]1[C:24]2[C:20](=[CH:19][CH:18]=[CH:17][C:16]=2[NH:2][S:1]([C:5]2[CH:6]=[CH:7][C:8]([SH:11]=[O:13])=[CH:9][CH:10]=2)(=[O:3])=[O:4])[CH:21]=[CH:22]1参加物
3
実験手順
767 mg (3.0 mmol) of 4-sulfamoylbenzenesulfonyl chloride was reacted with 264 mg (2.0 mmol) of 7-amino-1H-indole and treated, to give 445 mg of N-(1H-indole-7-yl)-4-sulfanoylbenzenesulfonamide. The resulting compound was chlorinated using N-chlorosuccinimide in dichloromethane, to give 349 mg of the title compound.
後処理
- additiontreated
出典と根拠
- ORDレコード
- ord-d24f49b68bf944d79c2e8a820fc732a0
- 出典データセット
- uspto-grants-2010_11
- 特許番号
- US07834049B2
関連ノート
読み込み中…