3,5-Dimethyl-2-hydroxymethyl-4-methoxy-pyridine → 4-Methoxy-3,5-dimethylpyridine-2-carbaldehyde
反応式
[CH3:1][O:2][C:3]1[C:8]([CH3:9])=[CH:7][N:6]=[C:5]([CH2:10][OH:11])[C:4]=1[CH3:12]>C(Cl)(Cl)Cl.[O-2].[O-2].[Mn+4]>[CH3:1][O:2][C:3]1[C:8]([CH3:9])=[CH:7][N:6]=[C:5]([CH:10]=[O:11])[C:4]=1[CH3:12]参加物
4
実験手順
(4-methoxy-3,5-dimethyl-pyridin-2-yl)methanol (Tokyo Kasei Kogyo Co., Ltd.) (300 mg) was dissolved in chloroform (15 ml) and added with manganese dioxide (chemically processed product) (3.00 g), followed by stirring for 3 hours. After completion of the reaction, the solution was filtrated through Celite and the solvent was then distilled off, thereby obtaining the subject compound (297 mg) as a white solid.
後処理
- customAfter completion of the reaction
- filtrationthe solution was filtrated through Celite
- distillationthe solvent was then distilled off
出典と根拠
- ORDレコード
- ord-4457e284cc134cc48ff5ad66aa3e81fc
- 出典データセット
- uspto-grants-2010_11
- 特許番号
- US07833991B2
反応ノート
読み込み中…