5-(azetidin-1-ylcarbonyl)-N-(tert-butyl)furan-2-sulfonamide → 5-(Azetidin-1-ylcarbonyl)furan-2-sulfonamide
反応式
[N:1]1([C:5]([C:7]2[O:11][C:10]([S:12]([NH:15]C(C)(C)C)(=[O:14])=[O:13])=[CH:9][CH:8]=2)=[O:6])[CH2:4][CH2:3][CH2:2]1>FC(F)(F)C(O)=O>[N:1]1([C:5]([C:7]2[O:11][C:10]([S:12]([NH2:15])(=[O:14])=[O:13])=[CH:9][CH:8]=2)=[O:6])[CH2:4][CH2:3][CH2:2]1参加物
3
実験手順
A solution of 5-(azetidin-1-ylcarbonyl)-N-(tert-butyl)furan-2-sulfonamide (the product of step ii) (3 g) in trifluoroacetic acid (90 mL) was stirred at room temperature. After 18 h the mixture was evaporated to dryness in vacuo. The resulting oil was triturated with Et2O and filtered to give the subtitle compound as a white solid. Yield: 1.75 g.
後処理
- customAfter 18 h the mixture was evaporated to dryness in vacuo
- customThe resulting oil was triturated with Et2O
- filtrationfiltered
出典と根拠
- ORDレコード
- ord-056147883c8e4d119a0209b7ab3989ac
- 出典データセット
- uspto-grants-2010_11
- 特許番号
- US07838675B2
反応ノート
読み込み中…