N-[2-(2-nitrophenyl)ethyl]acetamide → HCID 19593725、化合物

HRID 1176269ノート

反応式

HRID 1176269 の反応式
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[CH2:10][CH2:11][NH:12][C:13](=[O:15])[CH3:14])([O-])=O>C(O)C.[Pd]>[NH2:1][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[CH2:10][CH2:11][NH:12][C:13](=[O:15])[CH3:14]

参加物

4

反応物 1

HCID 2750518N-[2-(2-nitrophenyl)ethyl]acetamide

生成物 1

HCID 19593725HCID 19593725、化合物

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

A solution of 0.95 g of N-[2-(2-nitrophenyl)ethyl]acetamide in 30 ml of ethanol is hydrogenated in the presence of 0.112 g of 10% Pd/C at room temperature over 3.5 hours. The reaction mixture is clarified by filtration and the filtrate is concentrated by evaporation. The crude title compound is obtained as a light brown solid from the residue. Rf=0.50 (9:1 dichloromethane-methanol); Rt=1.86.

後処理

  1. filtrationThe reaction mixture is clarified by filtration
  2. concentrationthe filtrate is concentrated by evaporation

出典と根拠

ORDレコード
ord-fdbc214fcf964759b7aca0fa321b43b0
出典データセット
uspto-grants-2010_11
特許番号
US07842688B2

反応ノート

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