Cesium fluoride → Methyl 1-((3-fluoro-4-(5-(1-(4-fluorophenyl)vinyl)thiazolo[5,4-b]pyridine-2-yl)phenyl)methyl)azetidine-3-carboxylate

反応式

[F-].[Cs+].Cl[C:4]1[N:9]=[C:8]2[S:10][C:11]([C:13]3[CH:18]=[CH:17][C:16]([CH2:19][N:20]4[CH2:23][CH:22]([C:24]([O:26][CH3:27])=[O:25])[CH2:21]4)=[CH:15][C:14]=3[F:28])=[N:12][C:7]2=[CH:6][CH:5]=1.C([Sn](CCCC)(CCCC)[C:34]([C:36]1[CH:41]=[CH:40][C:39]([F:42])=[CH:38][CH:37]=1)=[CH2:35])CCC>CN(C=O)C.CCOC(C)=O.[Cu]I.[Pd].C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1>[F:28][C:14]1[CH:15]=[C:16]([CH2:19][N:20]2[CH2:23][CH:22]([C:24]([O:26][CH3:27])=[O:25])[CH2:21]2)[CH:17]=[CH:18][C:13]=1[C:11]1[S:10][C:8]2[C:7]([N:12]=1)=[CH:6][CH:5]=[C:4]([C:34]([C:36]1[CH:41]=[CH:40][C:39]([F:42])=[CH:38][CH:37]=1)=[CH2:35])[N:9]=2