反応式
[F:1][C:2]([F:12])([F:11])[C:3]1[CH:10]=[CH:9][CH:8]=[CH:7][C:4]=1[CH2:5]O.[BrH:13]>O>[F:1][C:2]([F:12])([F:11])[C:3]1[CH:10]=[CH:9][CH:8]=[CH:7][C:4]=1[CH2:5][Br:13]参加物
4
実験手順
A solution of 2-trifluoromethyl benzyl alcohol (1 g, 5.67 mmol) in aqueous HBr (6 mL) was stirred at 50° C. for 4 hrs. The reaction mixture was diluted with cold water and the product extracted with ethyl acetate. The organic layer was washed with saturated brine solution, dried over sodium sulphate and concentrated to afford 780 mg of 2-trifluoromethylbenzyl bromide.
後処理
- extractionthe product extracted with ethyl acetate
- washThe organic layer was washed with saturated brine solution
- dry with materialdried over sodium sulphate
- concentrationconcentrated
出典と根拠
- ORDレコード
- ord-de488eae72364be98e4a6cd3d7e791fe
- 出典データセット
- uspto-grants-2010_11
- 特許番号
- US07842696B2
関連ノート
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