N-bromobutanimide → HCID 178526566、化合物

HRID 1180874

反応式

HRID 1180874 の反応式
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([C:10]2[NH:14][N:13]=[CH:12][CH:11]=2)=[CH:6][CH:5]=1)([O-:3])=[O:2].[Br:15]N1C(=O)CCC1=O>CN(C)C=O>[Br:15][C:11]1[C:10]([C:7]2[CH:6]=[CH:5][C:4]([N+:1]([O-:3])=[O:2])=[CH:9][CH:8]=2)=[N:14][NH:13][CH:12]=1

参加物

4

反応物 2

HCID 67184N-bromobutanimideHCID 27370713-(4-Nitrophenyl)-1H-pyrazole

生成物 1

HCID 178526566HCID 178526566、化合物収率 90%

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

実験手順

A solution of 5-(4-nitrophenyl)-1H-pyrazole (595 mmol) in N,N-dimethylformamide (1000 mL) was treated with N-bromosuccinimide (654 mmol). The reaction stirred for 30 min at room temperature and was poured into ice-water (1000 mL). Product precipitated out of solution, was filtered, washed with water (4×500 mL) and dried to provide the title product as an off-white powder (90%). ESMS [M+H]+: 269.2

後処理

  1. customProduct precipitated out of solution
  2. filtrationwas filtered
  3. washwashed with water (4×500 mL)
  4. customdried

出典と根拠

ORDレコード
ord-204a52277c6749b685271428e0447013
出典データセット
uspto-grants-2007_10
特許番号
US07282588B2

関連ノート

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