Tert-butyl 2-(3-cyanobenzylidene)-1-hydrazinecarboxylate → Tert-butyl 2-(3-cyanobenzyl)hydrazinecarboxylate

HRID 1181189

反応式

HRID 1181189 の反応式
[C:1]([C:3]1[CH:4]=[C:5]([CH:16]=[CH:17][CH:18]=1)[CH:6]=[N:7][NH:8][C:9]([O:11][C:12]([CH3:15])([CH3:14])[CH3:13])=[O:10])#[N:2]>CO.[Pd]>[C:1]([C:3]1[CH:4]=[C:5]([CH:16]=[CH:17][CH:18]=1)[CH2:6][NH:7][NH:8][C:9]([O:11][C:12]([CH3:13])([CH3:14])[CH3:15])=[O:10])#[N:2]

参加物

4

反応物 1

HCID 69314844Tert-butyl 2-(3-cyanobenzylidene)-1-hydrazinecarboxylate

生成物 1

HCID 11831759Tert-butyl 2-(3-cyanobenzyl)hydrazinecarboxylate収率 95%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 887Methanol溶媒

実験手順

tert-Butyl 2-(3-cyanobenzylidene)-1-hydrazinecarboxylate (60.0 mmol) was dissolved in MeOH (250 mL) and 10% Pd/C (10 w/w %) was added. The mixture was hydrogenated for 6 h. The catalyst was filtered off and the filtrate was evaporated in vacuo to yield oily tert-butyl 2-(3-cyanobenzyl)-1-hydrazinecarboxylate which crystallized overnight.

後処理

  1. filtrationThe catalyst was filtered off
  2. customthe filtrate was evaporated in vacuo

出典と根拠

ORDレコード
ord-931d97faaac748029114674e6154f725
出典データセット
uspto-grants-2007_10
特許番号
US07285547B2

関連ノート

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