Hydrazine hydrate (1:1) → HCID 21960236、化合物

HRID 1181264

反応式

HRID 1181264 の反応式
[Cl:1][C:2]1[C:3]2[S:10][CH:9]=[C:8]([CH3:11])[C:4]=2[N:5]=[CH:6][N:7]=1.O.[NH2:13][NH2:14]>C(O)C>[ClH:1].[CH3:11][C:8]1[C:4]2[N:5]=[CH:6][N:7]=[C:2]([NH:13][NH2:14])[C:3]=2[S:10][CH:9]=1

参加物

4

反応物 2

HCID 24654Hydrazine hydrate (1:1)HCID 27775864-Chloro-7-methylthieno(3,2-d)pyrimidine

生成物 1

HCID 21960236HCID 21960236、化合物収率 88%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

A suspension of 4-chloro-7-methylthieno[3,2-d]pyrimidine (4, 3.1 g, 17 mmol) and hydrazine monohydrate (3.5 mL, 72 mmol) in ethanol (34 mL) was heated at reflux for 1 hour. After cooling to room temperature, the solid product was collected by vacuum filtration to give (7-methylthieno[3,2-d]pyrimidin-4-yl)hydrazine hydrochloride (3.2 g, 88% yield) as a white solid.

後処理

  1. temperaturewas heated
  2. temperatureat reflux for 1 hour
  3. filtrationthe solid product was collected by vacuum filtration

出典と根拠

ORDレコード
ord-39a22508340f48f6a4f3eb4aa3f801b3
出典データセット
uspto-grants-2007_10
特許番号
US07285556B2

関連ノート

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