Sodium Hydroxide → HCID 67362326、化合物
反応式
C[O:2][C:3]([C:5]1[CH:9]=[C:8]([O:10][CH2:11][CH:12]2[CH2:14][CH2:13]2)[N:7]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=2[F:21])[N:6]=1)=[O:4].[OH-].[Na+]>CO>[CH:12]1([CH2:11][O:10][C:8]2[N:7]([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=3[F:21])[N:6]=[C:5]([C:3]([OH:4])=[O:2])[CH:9]=2)[CH2:13][CH2:14]1参加物
4
実験手順
The crude compound obtained in step 1 was dissolved in 10 ml of methanol. 1.4 ml of an aqueous 1 M solution of sodium hydroxide were added and the mixture was stirred overnight at room temperature. The solvent was removed in vacuo and the residue purified by preparative HPLC to give 102 mg (58%) of the title compound
後処理
- customThe solvent was removed in vacuo
- customthe residue purified by preparative HPLC
出典と根拠
- ORDレコード
- ord-b9687e65b3084772ba68d088d01d04eb
- 出典データセット
- uspto-grants-2014_03
- 特許番号
- US08664257B2
反応ノート
読み込み中…