Nitrogen → HCID 86664910、化合物

HRID 1189383ノート

反応式

HRID 1189383 の反応式
N#N.[CH2:3]([C:5]1[O:6][C:7]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[C:8]([C:10](O)=[O:11])[N:9]=1)[CH3:4].CN(C=O)C.C(Cl)(=O)C([Cl:27])=O>C1(C)C=CC=CC=1>[CH2:3]([C:5]1[O:6][C:7]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[C:8]([C:10]([Cl:27])=[O:11])[N:9]=1)[CH3:4]

参加物

6

反応物 4

HCID 947NitrogenHCID 6228DimethylformamideHCID 65578Oxalyl chlorideHCID 669290412-Ethyl-5-phenyl-oxazole-4-carboxylic acid

生成物 1

HCID 86664910HCID 86664910、化合物

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

In a flame dried round-bottomed flask equipped with a magnetic stir bar and under inert atmosphere (N2), a suspension of 2-ethyl-5-phenyl-oxazole-4-carboxylic acid (54 mg, 0.25 mmol) in toluene (1.0 mL) was treated with a drop of DMF followed by oxalyl chloride (0.08 mL, 0.86 mmol) and the resulting yellow solution was stirred at rt for 30 min. The solvent was then removed under reduced pressure (coevaporation with toluene) to give 2-ethyl-5-phenyl-oxazole-4-carbonyl chloride.

後処理

  1. customThe solvent was then removed under reduced pressure (coevaporation with toluene)

出典と根拠

ORDレコード
ord-05b66699d4c54163a17d1a96e04fa562
出典データセット
uspto-grants-2014_03
特許番号
US08674111B2

反応ノート

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